Diphenhydramine/zinc (On the skin)
Diphenhydramine (dye-fen-HYE-dra-meen), Zinc, Zinc Acetate (zink AS-e-tate), Zinc Oxide (zink OX-ide)
Treats pain and itching caused by insect bites, minor cuts or burns, or sunburn. Also treats skin rash caused by poison ivy, poison oak, or poison sumac.
Brand Name(s):There may be other brand names for this medicine.
When This Medicine Should Not Be Used:You should not use this medicine if you have had an allergic reaction to diphenhydramine or zinc. Do not use this medicine for chickenpox or measles. Do not use on large areas of skin, or on rash areas that have blisters or broken skin. You should not use this medicine if you are also taking diphenhydramine (Benadryl®) by mouth.
How to Use This Medicine:
Stick, Lotion, Gel/Jelly, Spray, Cream, Ointment
- Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to.
- If you are using this medicine without a prescription, follow the instructions on the medicine label.
- Do not apply the medicine more than 4 times each day.
- This medicine is for use on the skin only. Do not get it in your eyes, nose, or mouth. Do not use it on skin areas that have cuts or scrapes. If it does get on these areas, rinse it off right away.
- Wash your hands with soap and water before and after using this medicine.
- Apply a thin layer to the affected area. Rub it in gently. Press tip of stick on affected skin area until liquid medicine flows, then dab lightly.
- Do not cover the treated area with a bandage unless your doctor has told you to.
If a dose is missed:
- If you miss a dose or forget to use your medicine, apply it as soon as you can. If it is almost time for your next dose, wait until then to apply the medicine and skip the missed dose. Do not apply extra medicine to make up for a missed dose.
How to Store and Dispose of This Medicine:
- Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
- The stick form of this medicine is flammable. Keep the medicine away from fire or open flame.
- Ask your pharmacist, doctor, or health caregiver about the best way to dispose of the used medicine container and any leftover medicine after you have finished your treatment. You will also need to throw away old medicine after the expiration date has passed.
- Keep all medicine away from children and never share your medicine with anyone.
Drugs and Foods to Avoid:
Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.
- Do not use cosmetics or other skin care products on the treated skin areas.
Warnings While Using This Medicine:
- Make sure your doctor knows if you are pregnant or breast feeding.
- If your symptoms do not improve or if they get worse, call your doctor.
Possible Side Effects While Using This Medicine:
Call your doctor right away if you notice any of these side effects:
- Worsened skin rash, itching, redness, or swelling.
If you notice these less serious side effects, talk with your doctor:
- Return of your skin symptoms a few days after they have cleared up.
If you notice other side effects that you think are caused by this medicine, tell your doctor
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088Last Updated:
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